

Help Their Heart When Problems Start
Pro Plan Veterinary Diets CC CardioCare represents a novel dietary therapy that targets metabolomic changes in dogs with early stages of canine mitral valve disease.
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Supported by a Six-Month Study
Learn about a blinded randomized placebo-controlled study of the Cardiac Protection Blend in CC CardioCare.


See the Metabolomics Data
Read about the science behind the Cardiac Protection Blend in CC CardioCare.


Explore Metabolic Pathways with Purina Scientists
Visit the Purina Institute to read related research from Purina scientists about metabolomics and cardiac conditions.


Diet Effects on Metabolome in Canine Myxomatous Mitral Valve Disease
A six-month dietary intervention demonstrated efficacy of Cardiac Protection Blend in slowing MMVD progression in dogs.


Gut Dysbiosis in Canine Myxomatous Mitral Valve Disease
The aim of the study is to evaluate gut microbial dysbiosis and its relationship with gut-produced metabolites in dogs with MMVD.


Diet Reduces Left Atrial Enlargement in Dogs with Early Preclinical MMVD
Dietary intervention reduces left atrial enlargement in dogs with early preclinical myxomatous mitral valve disease: a blinded randomized controlled study in 36 dogs.


Metabolomics in Canine Myxomatous Mitral Valve Disease
Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease


Mitral Valve Disease in Dogs
Veterinary Medicine and Multi-Omics Research for Future Nutrition Targets: Metabolomics and Transcriptomics of the Common Degenerative Mitral Valve Disease in Dogs